Tesamorelin, a synthetic peptide analogue of growth hormone-releasing hormone (GHRH), has been widely studied for its potential therapeutic applications, particularly in the context of HIV-associated lipodystrophy (HALS). It consists of 44 amino acids and functions by stimulating the pituitary gland to produce and secrete growth hormone (GH).
According to research, Tesamorelin can significantly reduce visceral adipose tissue (VAT) leading to improved lipid profiles and insulin sensitivity, suggesting potential benefits for cardiovascular health.
Tesamorelin has also been shown to increase IGF-1 (Insulin-like Growth Factor 1) levels, which Luxembourg research suggests is beneficial for muscle growth, recovery, and overall metabolic function.
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[1] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC6766405/
[2] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC4601733/
[3] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC8243807/
[4] https://pubmed.ncbi.nlm.nih.gov/ 21668043/
[5] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC5633509/
[6] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC3673013/
[7] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC3513535/
[8] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC3038486/
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